Does a Sony camera motherboard require custom calibration after?

Does a Sony mirrorless camera motherboard swap require custom calibration steps afterwards?

I have a Sony a6500 with mainboard damage and before buying a replacement mainboard the seller told me that it's possible the mainboard will require additional calibration and adjustment steps that are custom to the camera body that I have.

They said sometimes it might require focus adjustment and long exposure noise suppression adjustments.

Has anyone else encountered this while repairing Sony mirrorless cameras? It sounds like it's not a simple replacement and might need more dedicated hardware and software.