Home button doesnt work after cleaning charging port with isopropyl

Firstly try opening the phone and making sure everything inside is fine. Clean all of the connectors with the iso and then make sure it’s all firmly plugged in before trying to power on again. If you’re still having no luck with it, then you may need to get a third-party replacement button, but be aware any replacement home button will only function for the click, and TouchID will no longer work.

An alternative could be to use the assistive touch feature instead of physically clicking the home button. Personally I would rather be able to unlock the phone with the TouchID, even if the actual click of the button didn’t work, but up to your preference.