Don’t you enjoy the interruptions? ;-}
Sadly all you can do is if your phone allows you to block the number thats about it directly.
The best way it to look at your carrier for relief. You may need to change to one that offers blocking. When they see a common number spitting out lots of calls they check it out and then block it and any other numbers linked to that person (company). They also block VoIP calls as well as these can be spoofed.
Even that is not foolproof! You’ll still get a few but a lot less!