I was completely unable to get the screw directly over the homebutton off. I definitely stripped it some. Here’s some tips!
1. If you are trying to unscrew and it skips instead of locking in—STOP. Apply more pressure, and then try again. Keep doing this until it comes out. If you continue turning without doing anything, you’ll strip the head of the screw and end up in a way worse situation.
2. If your screw is stripped, first try putting a rubber band between the screwdriver and the screw to fill the gap. Duct tape has worked for many people as well.
3. If you can’t get the screw directly above the home button off of the home button, I found this video that shows how to remove the home button without unscrewing the screw!! Bend the protective plate up 90° on both sides of the home button so the bent plate now fits through the home button hole. Then you can continue to
the next steps and remove the home button with the plate still attached to it.